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金合歡素

分析標(biāo)準(zhǔn)品,HPLC≥98%

Acacetin

CAS號：480-44-4

分子式：C16H12O5

分子量：284.26

MDL：MFCD00016936

別名：刺槐素

產(chǎn)品介紹

熔點(diǎn)：260-265 ℃

沸點(diǎn)：518.6 ℃ at 760 mmHg

外觀：黃色針狀結(jié)晶

溶解性：DMSO：60mg/ml

儲存條件：2-8℃

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(25篇)

25. [IF=3.8] Jialu Shen et al."Insights into inhibitory mechanisms: Unraveling the structure-activity relationship of dietary flavonoids on gut bacterial β-glucuronidase."Journal of Functional Foods.2024 Nov;122:106510

24. [IF=6.7] Wenshuang Wang et al."Acacetin alleviates rheumatoid arthritis by targeting HSP90 ATPase domain to promote COX-2 degradation."PHYTOMEDICINE.2024 Oct;:156171

23. [IF=5.1] Yiwei Yuan et al."Chrysanthemum extract mitigates high-fat diet-induced inflammation, intestinal barrier damage and gut microbiota disorder."Food & Function.2025 Jan;:

22. [IF=4.9] Man Zhang et al."Systematic Identification and Characterization of O-Methyltransferase Gene Family Members Involved in Flavonoid Biosynthesis in Chrysanthemum indicum L.."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2024 Jan;25(18):10037

21. [IF=5.1] Jing-Qun Liu et al."Apigenin ameliorates lupus nephritis by inhibiting SAT3 signaling in CD8+T cells."Food & Function.2024 Sep;:

20. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal

19. [IF=5.9] Yadi Gao et al."Multiplex approach of metabolite and transcript profiling identify a biosynthetic mechanism for kayaflavone biosynthesis in Torreya grandis."INDUSTRIAL CROPS AND PRODUCTS".2024 Aug;214:118482

18. [IF=8.7] Yuan Ziyu et al."Four novel Cit7GlcTs functional in flavonoid 7-O-glucoside biosynthesis are vital to flavonoid biosynthesis shunting in citrus."Horticulture Research".2024 Apr;:

17. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038

16. [IF=4.1] Liangliang He et al."A multi-module structure labelled molecular network orients the chemical profiles of traditional Chinese medicine prescriptions: Xiaoyao San, as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Jan;1715:464613

15. [IF=3.4] Tongjie Xiao et al."In vitro bloodbrain barrier permeability study of four main active ingredients from Alpiniae oxyphyllae fructus."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Aug;:115637

14. [IF=7.419] Xueyan Li et al."Rapid screening and in vivo target occupancy quantitative evaluation of xanthine oxidase inhibitors based on drug-target binding kinetics research strategy: A case study of Chrysanthemum morifolium Ramat.."BIOMEDICINE & PHARMACOTHERAPY.20

13. [IF=3.192] Yuan, Peipei et al."Acacetin inhibits myocardial mitochondrial dysfunction by activating PI3K/AKT in SHR rats fed with fructose."Journal of Natural Medicines.2022 Dec;:1-14

12. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

11. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

10. [IF=4.36] Zhenhui Guo et al."Study on the mechanism of Cortex Lycii on lung cancer based on network pharmacology combined with experimental validation."J Ethnopharmacol. 2022 Apr;:115280

9. [IF=7.46] Shuo Wang et al."A novel visual sensing method based on Al@AuNCs for rapid identification of Chrysanthemum morifolium from different origins."Sensor Actuat B-Chem. 2022 Apr;356:131307

8. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621

7. [IF=1.402] Wei  Yaxin et al."Acacetin improves endothelial dysfunction and aortic fibrosis in insulin-resistant SHR rats by estrogen receptors."Mol Biol Rep. 2020 Sep;47(9):6899-6918

6. [IF=5.645] Yanfengyang Jiang et al."Gene mining and identification of a flavone synthase II involved in flavones biosynthesis by transcriptomic analysis and targeted flavonoid profiling in Chrysanthemum indicum L.."Ind Crop Prod. 2019 Aug;134:244

5. [IF=4.411] Li Jia et al."Systematic Profiling of the Multicomponents and Authentication of Erzhi Pill by UHPLC/Q-Orbitrap-MS Oriented Rapid Polarity-Switching Data-Dependent Acquisition and Selective Monitoring of the Chemical Markers Deduced from Fingerprint Analys

4.  Jiang, Yanfengyang, et al. "Gene mining and identification of a flavone synthase II involved in flavones biosynthesis by transcriptomic analysis and targeted flavonoid profiling in Chrysanthemum indicum L." Industrial Crops and Products 134 (2019): 244-256

3.  莉莉,陳勇,張蒙偉,鄢紅霞,高守紅,陳萬生.UHPLC-MS/MS法測定新冠肺炎經(jīng)驗方寒濕郁肺湯中11種主成分的含量[J].藥學(xué)實踐雜志,2021,39(02):148-151+156.

2.  韓星, 李雪巖, 楊海洋,等. 菊花水提物的質(zhì)量控制成分篩選及其網(wǎng)絡(luò)藥理學(xué)作用研究[J]. 中國藥房, 2019, 030(023):3258-3265.

1.  胡瑞瑞, 王利, 張紅芹. 金合歡素聚乳酸納米粒的制備及體內(nèi)藥動學(xué)評價[J]. 中藥材, 2018, 041(005):1170-1172.

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